Danke für den Tip aber das meinte ich mit "in kleinen Mengen sehr teuer" 31,54 EUR für 25g. Im Liter Arbeitslösung des Ansco 130 sind 5,5g Glycin, macht 6,69 EUR nur fürs Glycin, der Rest ist preislich vernachlässigbar. In Amerika kostet das Pfund etwa 79$. Sollte die Synthese wirklich so einfach sein, wie in dem alten Text beschrieben, wäre es selbst noch viel günstiger herzustellen. Hier der Wortlaut. Die genaue Quellenangaben habe ich leider nicht auf der Kopie notiert:
Titel: Asymtric Quinquevalent Nitrogen Compounds III. S. 551 f.
Attemts to Prepare Asymmetric Quinquevalent Nitrogen Compounds. Part III. Hydroxyphenylglicine.
By (the late) Raphael Meldola, Henry Stennett Foster, and Rainald Brightman.
S. 552 Abs. 2 Experimental
p-Hydroxyphenylglicine
Vater (J. pr. Chem., 1884,(ii), 29, 286) obtained the compound by digesting one molecular proportion of monochloroacetic acid with two molecular proportions of p-aminophenol and 20 parts of water. We found that a better yield was obtained by using molecular proportions of p-aminophenol (3 gr), monochloroacetic acid (2,6 gr.), and sodium acetate (4 gr.) in aqueous solution. The pink solid which separated was collected and crystallised from water, from wich it separated only on stirring in a somewhat flocculent form. (Found, N=8,42. Calc., N= 8,39 per cent.)
....
Am Ende des Absatzes steht: Finbury Technical College (Recieved, April 25th, 1917.)
Mir ist noch nicht klar, was N=8,42 bzw N=8,39 per cent bedeutet.
Schönen Abend
Titel: Asymtric Quinquevalent Nitrogen Compounds III. S. 551 f.
Attemts to Prepare Asymmetric Quinquevalent Nitrogen Compounds. Part III. Hydroxyphenylglicine.
By (the late) Raphael Meldola, Henry Stennett Foster, and Rainald Brightman.
S. 552 Abs. 2 Experimental
p-Hydroxyphenylglicine
Vater (J. pr. Chem., 1884,(ii), 29, 286) obtained the compound by digesting one molecular proportion of monochloroacetic acid with two molecular proportions of p-aminophenol and 20 parts of water. We found that a better yield was obtained by using molecular proportions of p-aminophenol (3 gr), monochloroacetic acid (2,6 gr.), and sodium acetate (4 gr.) in aqueous solution. The pink solid which separated was collected and crystallised from water, from wich it separated only on stirring in a somewhat flocculent form. (Found, N=8,42. Calc., N= 8,39 per cent.)
....
Am Ende des Absatzes steht: Finbury Technical College (Recieved, April 25th, 1917.)
Mir ist noch nicht klar, was N=8,42 bzw N=8,39 per cent bedeutet.
Schönen Abend
